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Public filings / SYRE on Yahoo Finance (opens in a new tab)

SYRE: insider buying, 13F holders, analyst moves

Spyre Therapeutics Inc - US

A summary of public filings about Spyre Therapeutics Inc - US. For the latest insider history, price chart, analyst changes and activist filings, open the live lookup.

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SEC Form 13F · Q2 2026

4 of our 100 managers hold SYRE

Combined reported value $796.7M; 2 sold out since Q1 2026.

Holders among our 100 managers: 2 in Q3 2023, 4 in Q2 2026.

ManagerValue% of portfolioChange vs Q1 2026
Perceptive Advisors$383.5M5.95%Added
RTW Investments$377.5M3.22%Added
Samlyn Capital$35.5M0.59%Added
Tudor Investment$235K0.00%Trimmed

All holders and who sold out

Important information

Facts from public SEC filings, shown for information only. Not a recommendation. Not individualized investment advice. Gulfstream Capital and its clients may hold positions in securities shown.